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Can we reduce the number of fish in the OECD acute toxicity test? 

Authors: Hans Rufli, Timothy A Springer

Source: Environmental toxicology and chemistry / SETAC. 2011 Apr  pdf-file

The chironomid acute toxicity test: development of a new test system.

Authors: Lennart Weltje, Hans Rufli, Fred Heimbach, James Wheeler, Marco Vervliet-Scheebaum, Michael Hamer

Source: Integrated environmental assessment and management. 2010 Apr   pdf-file

Environmental effect assessment for sexual endocrine-disrupting chemicals: Fish testing strategy.

Authors: Thomas Knacker, Melanie Boettcher, Tobias Frische, Hans Rufli, Hans-Christian Stolzenberg, Matthias Teigeler, Sabine Zok, Thomas Braunbeck, Christoph Schäfers

Source: Integrated environmental assessment and management. 2010 Oct   pdf-file

Multi-criteria decision analysis of test endpoints for detecting the effects of endocrine active substances in fish full life cycle tests.

Authors: Mark Crane, Melanie Gross, Peter Matthiessen, Gerald T Ankley, Stephen Axford, Poul Bjerregaard, Ross Brown, Peter Chapman, Michael Dorgeloh, Malyka Galay-Burgos,…

Source: Integrated environmental assessment and management. 2010 Jul  pdf-file

The use of fish cells in ecotoxicology. The report and recommendations of ECVAM Workshop 47.

Authors: Argelia Castaño, Niels Bols, Thomas Braunbeck, Paul Dierickx, Marlies Halder, Boris Isomaa, Kazumi Kawahara, Lucy E J Lee, Carmel Mothersill, Peter Pärt,…

Source: Alternatives to laboratory animals : ATLA. 2003 May-Jun    pdf-file

Determination of vitellogenin kinetics in male fathead minnows (Pimephales promelas).

Authors: T Schmid, J Gonzalez-Valero, H Rufli, D R Dietrich

Source: Toxicology letters. 2002 May 10    pdf-file

Aquatic toxicity testing of sparingly soluble, volatile, and unstable substances and interpretation and use of data. Task Force of the European Centre for Ecotoxicology and Toxicology of Chemicals.

Authors: H Rufli, P R Fisk, A E Girling, J M King, R Länge, X Lejeune, N Stelter, C Stevens, P Suteau, J Tapp,…

Source: Ecotoxicology and environmental safety. 1998 Feb    pdf-file                                                   

Aquatic toxicity testing of sparingly soluble and volatile substances

Authors: H Rufli, P R Fisk, A E Girling, J M King, R Länge, X Lejeune, N Stelter, C Stevens, P Suteau, J Tapp,…

Source: ECETOC Monograph No. 26. 1996 Sept    pdf-file

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Expertise of Hans Rufli, Dr. sc. nat. ETH

Year Position
2006-date Adviser in Ecotoxicology to the Korea Institute of Toxicology
1994-2003

Head of Aquatic Ecology Team, Novartis and Syngenta Crop Protection AG, Basel, Switzerland

1989-1994 Project Leader of Biomonitoring-Aquatox, Ciba-Geigy AG, Basel, Switzerland
1982-1989 Study Director in Ecotoxicology, Ciba-Geigy AG, Basel, Switzerland
1981-1982 Limnologist / Biologist, Laboratory for Environmental Research,
Istituto cantonale batterioseriologico, Lugano, Switzerland
1978-1980 Head of Department / Fishery Biologist, Lake Malawi Fishery Expansion Project, *FAO , Malawi, Africa
1977-1978 Head of Department / Fishery Biologist in Aquaculture, Brackishwater Aquaculture Development Centre, *FAO, Java, Indonesia
1975-1977 Head of Department / Fishery Biologist, Lake Tanganyika Fishery Research & Development Project, *FAO, Tanzania, Africa
1969-1974 Research Assistant in Fishery Science, Swiss Federal Institute of Aquatic Science and Technology, ETH / EAWAG, Switzerland
   

Participation at Meetings of International Organizations

Year Event
2003

*ICCA Endocrine Coordination Meetings

2001-2008 *VCI Working Group ‘Ecological Methods’, Task Force ‚Endocrine Effects’
2001-2007 *ECPA/IVA Task Force ‘Endocrine Disruptors’
2001-2003 *CEFIC *EMSG LRI Monitoring Team of the ‘Aquatic Research Programme of the Chronic Effects of Endocrine Disruptors to Fish’
2001-date *OECD Expert Consultation on Endocrine Disruptors Testing in Fish and Amphibians, Fish Testing Framework, Test Guidelines Programme
2001 *ECVAM Expert Consultation on ‘The Use of Fish Cells in Environmental
1997-date *SETAC Meetings giving Short Courses and Presentations

  

* Explanation of the Abbreviations used

FAO - Food and Agriculture Organisation of the United Nations

ICCA - International Council of Chemical Associates

VCI - German Chemical Industry Association

IVA - Industrieverband Agrar, Germany

ECPA - European Crop Protection Association

CEFIC - European Chemical Industry Council

OECD - Organisation for Economic Co-Operation and Development

ECVAM - European Center for the Validation of Alternative Methods

SETAC - Society of Environmental Toxicology and Chemistry

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